The Centre for the Studies of Asphyxia and Resuscitation

Grand Rounds, global trials, and closing the Karachi chapter Part 3 of the educational tour brought us to Aga Khan University Hospital , where the program was expertly organized and hosted by Dr. Ali Hussain and Dr. Waqar Khowaja . It was particularly meaningful to reconnect with Dr. Ali Hussain , a former neonatal fellow who trained in Edmonton, underscoring the strength of long-standing international training links and collaborations. Weekly Grand Rounds: from evidence to

Connecting practice, evidence, and experience across institutions Part 2 of the educational tour through Pakistan took us to two outstanding clinical centers, each offering a unique perspective on neonatal care while sharing a common commitment to improving outcomes for newborns. Stop 1: Liaquat National Hospital The first visit of the day was to Liaquat National Hospital and Medical College and was expertly organized by the local team. We met with an engaged and highly expe

Learning together to strengthen neonatal care Today marked the beginning of an inspiring educational tour through Pakistan. I had the privilege of visiting the Sindh Institute of Child Health and Neonatology , where I received a very warm welcome from Dr. Rehan , Dr. Raza , and their dedicated multidisciplinary team. I was invited by Fisher & Paykel Healthcare to join them for a week of education focused on neonatal resuscitation and non-invasive respiratory support, includi

What is already known Current neonatal resuscitation guidelines recommend delivering chest compressions (CC) over the lower third of the sternum , a recommendation largely derived from imaging studies in older infants and children , with very limited newborn-specific data. What this study adds Using transthoracic echocardiographic mapping in healthy term newborns , we found that the left ventricle (LV) is consistently located at the inter-nipple line along the 4th–5th left s

Vasopressin vs Epinephrine during cardiopulmonary resuscitation of asphyxiated newborns – a cluster randomized controlled phase I trial Introduction Current neonatal resuscitation guidelines recommend the use of epinephrine during neonatal cardiopulmonary resuscitation (CPR). However, newborns receiving epinephrine continue to have high rates of mortality and neurodevelopmental disability. The infrequent need for neonatal CPR, coupled with an inability to consistently anticip

Why this study matters During advanced neonatal cardiopulmonary resuscitation (CPR), clinicians often face a critical question: should volume be given early to support circulation, or is pharmacologic support with epinephrine superior? While volume expansion is recommended when hypovolemia is suspected, evidence supporting its use during CPR in euvolemic newborns remains limited. This experimental study used a near-term lamb model of severe asphyxia to directly compare rapid

We would like to congratulate all sites for recruiting 1100 of 1200 patients. Congratulations, what an achievement! Thank you to everyone involved and being part of the HiLo-journey and thanks to all the parents who have consented for their babies to be part of this trial. Oxygen is a vital element in the care of preterm infants and has been given more often than any other drug over the past 80 years. Despite this, we know very little about how much or how little oxygen is sa

We are pleased to welcome Sabah Binte Khorshed  to our team as part of the PMCOL 302 Pharmacology Tutorial . These research courses offer pharmacology specialization students the opportunity to gain hands-on laboratory and research experience, including experimental design, data analysis, literature review, and scientific presentation skills. Sabah’s project will focus on examining injury markers after vasopressin administration  during neonatal resuscitation. Her work will c

We are delighted to welcome Abibah Kromah to our team through BIOL 399A – Research Project in the Faculty of Science. This two-term course provides third-year students with the opportunity to carry out directed independent research under the supervision of a faculty member. Students gain hands-on experience in experimental design, data collection, and scientific communication, with successful completion requiring a written report on their research project . Abibah’s projec

We are pleased to welcome Grace Leaman to our team as part of her PMCOL 402 Pharmacology Tutorial research course. These courses provide pharmacology specialization students with independent, hands-on research experience. Students gain valuable training in laboratory techniques, data analysis, literature review, notebook maintenance, and presentation skills, culminating in an abstract and poster presentation . Grace’s project will focus on examining alternative approaches t