The Centre for the Studies of Asphyxia and Resuscitation

Closing the Gap: Improving Treatment for Patent Ductus Arteriosus in Tiny Preemies Every heartbeat counts in the early days of life — especially for our tiniest babies. The ductus arteriosus (DA) is a normal blood vessel in the fetus that connects the main artery of the heart (the pulmonary artery) to the aorta. This vessel allows blood to bypass the lungs before birth, since oxygen is supplied by the placenta. After birth, the DA naturally closes within 48 hours as the baby

The 2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care (Part 5: Neonatal Resuscitation ) mark a major evolution in newborn care. These updates emphasize prevention, preparation, teamwork, and recovery — recognizing that every stage from pregnancy to postnatal follow-up influences survival and long-term outcomes. 🔗 The “Newborn Chain of Care” A new framework called the Newborn Chai

The 2025 International Liaison Committee on Resuscitation (ILCOR) Consensus on Science with Treatment Recommendations (CoSTR) introduces several important updates to neonatal resuscitation practice — from preparation and cord management to airway, medication, and post-resuscitation care. Below is a summary of the most relevant changes and their implications for clinicians and researchers. 1. Team Preparation and Communication Effective neonatal resuscitation begins before bi

Introduction During the immediate transition from fetal to neonatal life, rapid physiological changes occur in cardiovascular and respiratory systems. For extremely and very preterm infants (<32 weeks’ gestation), these transitions are even more complex, yet normative reference values for vital parameters such as arterial oxygen saturation (SpO₂), heart rate (HR), and cerebral oxygenation (crSO₂) remain poorly defined. The COSGOD III trial (Cerebral regional tissue Oxygen Sa

Comparison of intravenous and intraosseous administration of vasopressin and epinephrine during cardiopulmonary resuscitation of asphyxiated neonatal piglets During neonatal cardiopulmonary resuscitation (CPR), every second counts . The timely delivery of vasopressors is vital, yet gaining vascular access—especially in a fragile newborn—can be a major barrier. Epinephrine remains the only recommended vasopressor, but vasopressin is emerging as a possible alternative , particu

We are pleased to announce that recruitment has been successfully completed for the VOLT-Trial (Volume Targeted Mask Ventilation Versus Pressure Ventilation in Preterm Infants – a randomized controlled trial) . About the Study This pilot randomized controlled trial enrolled 50 preterm infants (23–28 weeks’ gestation) who required respiratory support at birth. Infants were randomized to receive either pressure-guided mask ventilation or volume-targeted mask ventilation in

Background When a preterm baby is born, the first few minutes of life are critical. Many need help establishing breathing, and neonatal...

Delivering effective ventilation during neonatal resuscitation is one of the most critical—and technically challenging—skills in newborn...

Two visiting scholars, Ming (Shanghai) and CG (Shenzhen) , were in Edmonton Between Juen and August to participate in academic and...

I had the pleasure of hosting Professor Don Sharkey and Dr. Szed Taha at the Centre for the Studies of Asphyxia and Resuscitation (CSAR)...