The Centre for the Studies of Asphyxia and Resuscitation

Exploring alternative approaches to neonatal CPR Current neonatal resuscitation guidelines recommend using a 3:1 compression-to-ventilation ratio (3:1 C:V) during cardiopulmonary resuscitation (CPR). While this approach has been the standard for decades, important physiological questions remain regarding how best to combine ventilation and chest compressions during neonatal cardiac arrest. One concern with the 3:1 C:V technique is that interruptions for ventilation may contri

Over the last decade, our research program has focused on improving cardiopulmonary resuscitation (CPR) for newborn infants. Traditional neonatal CPR uses a 3:1 compression-to-ventilation ratio (3:1 C), but growing evidence suggests that alternative approaches may improve ventilation, circulation, and ultimately outcomes during resuscitation. Two promising techniques that have emerged from this work are: Chest Compressions with Sustained Inflation (CC+SI) Chest Compression Sy

Research often takes us across continents in pursuit of answers to some of the most important questions. This week, I am back at the Australian Synchrotron in Melbourne for another intensive period of research focused on understanding and ultimately identifying ways to reduce and preventing intraventricular hemorrhage (IVH) in extremely premature infants. This is not my first visit to the Synchrotron. Over the last years, I have returned several times to join a world leading

New International Survey Highlights Variations in Oxygen Management Around the World Bronchopulmonary dysplasia (BPD) remains one of the most common complications of extreme prematurity. Many infants with BPD require supplemental oxygen beyond their initial hospital stay, yet there is surprisingly little consensus on how oxygen therapy should be managed after discharge home. A new international survey involving clinicians from 44 countries provides valuable insight into curre

The Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates (MVP) Trial is officially underway, and we're excited to share that the study has launched with tremendous momentum. On the very first day of recruitment, four babies were enrolled, marking an impressive start for this important research initiative. The MVP Trial is investigating whether ventilator-delivered positive pressure ventilation (V-PPV) can improve

Respiratory Trajectories of the Most Preterm Infants: What Happens After Birth? 👶🫁 Understanding the respiratory journey of extremely premature infants is essential for improving care, guiding research, and helping families prepare for the challenges ahead. A newly published exploratory analysis from the international PLUSS Trial provides one of the most detailed descriptions to date of respiratory support from birth until discharge in infants born before 26 weeks’ gestatio

We would like to congratulate Marwa Ramsie for passing her PhD Thesis Defense: "Efficacy of Various Routes of Vasopressin Administration During Neonatal Resuscitation" and thereby her PhD! The Centre for the Studies of Asphyxia and Resuscitation (CSAR) and Research4Babies.org are proud to announce that Marwa Ramsie has passed her PhD Thesis Defense: “Efficacy of Various Routes of Vasopressin Administration During Neonatal Resuscitation” Neonatal cardiopulmonary resuscitation