The Centre for the Studies of Asphyxia and Resuscitation

We would like to congratulate all sites for recruiting 1150 of 1200 patients. Congratulations, what an achievement! Thank you to everyone involved and being part of the HiLo-journey and thanks to all the parents who have consented for their babies to be part of this trial. Oxygen is a vital element in the care of preterm infants and has been given more often than any other drug over the past 80 years. Despite this, we know very little about how much or how little oxygen is sa

Oxygen is a vital element in the care of preterm infants and has been given more often than any other drug over the past 80 years. Despite this, we know very little about how much or how little oxygen is safe particularly at birth. Preterm birth, or birth before 37 weeks’ gestation, is occurring in 8% of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before 29 weeks’ gestation. At this gestational age, t

From bench to bedside: translating physiology into clinical trials Cardiopulmonary resuscitation (CPR) at birth remains one of the most critical—and challenging—situations in neonatal care. While only a small proportion of newborns require CPR, the outcomes are sobering: mortality remains high, and survivors often face significant neurological injury. This blog highlights an important journey in neonatal resuscitation research— the development and translation of chest compres

Oxygen is a vital element in the care of preterm infants and has been given more often than any other drug over the past 80 years. Despite this, we know very little about how much or how little oxygen is safe particularly at birth. Preterm birth, or birth before 37 weeks’ gestation, is occurring in 8% of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before 29 weeks’ gestation. At this gestational age, t

I am delighted to share some fantastic news from our team at CSAR: Marwa Ramsie has successfully passed her PhD Candidacy Exam —a major milestone that marks her transition to independent doctoral research. \A focused and impactful PhD program Marwa’s PhD work centers on vasopressin as a potential alternative to epinephrine during neonatal cardiopulmonary resuscitation (CPR) . Her research addresses a critical gap in neonatal resuscitation science, combining rigorous physiolo

Oxygen is a vital element in the care of preterm infants and has been given more often than any other drug over the past 80 years. Despite this, we know very little about how much or how little oxygen is safe particularly at birth. Preterm birth, or birth before 37 weeks’ gestation, is occurring in 8% of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before 29 weeks’ gestation. At this gestational age, t

Providing effective and gentle respiratory support in the first minutes after birth is one of the most critical—and challenging—tasks in neonatal care. The VOLT trial (Volume-Targeted mask ventilation versus pressure ventilation in preterm infants) was designed to address a fundamental gap in delivery room practice: how to reliably deliver safe tidal volumes during positive pressure ventilation (PPV) immediately after birth. Why does this matter? When preterm infants fail to

Reflections, gratitude, and lasting impressions The educational tour through Pakistan was an intense, rewarding, and deeply meaningful experience. Over several days, I had the privilege of engaging with clinicians, nurses, educators, and leaders across multiple institutions in Karachi and Lahore, all united by a shared commitment to improving outcomes for newborn infants. Education, exchange, and collaboration The program focused on neonatal resuscitation and respiratory sup

Final stops: leadership, learning, and lasting connections The educational tour through Pakistan concluded with two meaningful and impactful visits in Lahore , bringing together academic leadership, bedside care, and practical discussions on neonatal respiratory support. Fatima Jinnah Medical University Our first visit was to Fatima Jinnah Medical University , where we were warmly received by the Vice Chancellor, Prof. Dr. Khalid Masood Gondal . The visit included the inaugur

Lahore: focused discussion, hands-on learning, and bedside exchange The educational tour continued on Thursday in Lahore , beginning with a compact, highly interactive meeting held at the Pearl Continental Hotel . Around 70 participants joined for a day dedicated to practical, evidence-informed neonatal respiratory care. Thursday: Conference and Workshops The program covered key themes across the continuum of care, including: Oxygen use at birth Neonatal resuscitation Nasal C