The Centre for the Studies of Asphyxia and Resuscitation

From bench to bedside: translating physiology into clinical trials Cardiopulmonary resuscitation (CPR) at birth remains one of the most critical—and challenging—situations in neonatal care. While only a small proportion of newborns require CPR, the outcomes are sobering: mortality remains high, and survivors often face significant neurological injury. This blog highlights an important journey in neonatal resuscitation research— the development and translation of chest compres

Grand Rounds, global trials, and closing the Karachi chapter Part 3 of the educational tour brought us to Aga Khan University Hospital , where the program was expertly organized and hosted by Dr. Ali Hussain and Dr. Waqar Khowaja . It was particularly meaningful to reconnect with Dr. Ali Hussain , a former neonatal fellow who trained in Edmonton, underscoring the strength of long-standing international training links and collaborations. Weekly Grand Rounds: from evidence to

What is already known Current neonatal resuscitation guidelines recommend delivering chest compressions (CC) over the lower third of the sternum , a recommendation largely derived from imaging studies in older infants and children , with very limited newborn-specific data. What this study adds Using transthoracic echocardiographic mapping in healthy term newborns , we found that the left ventricle (LV) is consistently located at the inter-nipple line along the 4th–5th left s

When a baby is born without enough oxygen, every second counts. Doctors and nurses jump into action, performing newborn CPR — chest compressions and small breaths — to try to restart the baby’s heart and breathing. Right now, international guidelines recommend a 3:1 compression-to-breath ratio , meaning caregivers give three quick chest compressions followed by one breath . But some researchers are exploring whether there’s a better way. 💡 A New Idea: Continuous Compressions

Meet the Data and Safety Monitoring Board (DSMB) for the SURV1VE-2 Trial Every clinical trial needs an independent team of experts whose...

Leading the Way in Newborn Resuscitation Research Behind every major clinical trial is a dedicated team of experts guiding the vision,...

Saving Newborn Lives: Rethinking CPR in the Delivery Room Every year, an estimated 2–3 million newborn babies around the world need...

Saving Newborn Lives: Rethinking CPR in the Delivery Room Every year, 2–3 million newborn babies around the world need cardiopulmonary...

Background Current neonatal resuscitation guidelines recommend a 3:1 chest compression/ventilation (C:V) ratio, but this approach has...

BACKGROUND To compare tidal volume (VT) delivery with compliance at 0.5 and 1.0 mL/cmH2O using five different ventilation (PPV) devices...