

Study Protocol SpotlightThe VOLT Trial: Volume-Targeted Mask Ventilation versus Pressure Ventilation in Preterm Infants
Providing effective and gentle respiratory support in the first minutes after birth is one of the most critical—and challenging—tasks in neonatal care. The VOLT trial (Volume-Targeted mask ventilation versus pressure ventilation in preterm infants) was designed to address a fundamental gap in delivery room practice: how to reliably deliver safe tidal volumes during positive pressure ventilation (PPV) immediately after birth. Why does this matter? When preterm infants fail to
Jan 293 min read


We have completed The VERSE-trial - Vasopressin vs Epinephrine during CPR of asphyxiated newborns
Vasopressin vs Epinephrine during cardiopulmonary resuscitation of asphyxiated newborns – a cluster randomized controlled phase I trial Introduction Current neonatal resuscitation guidelines recommend the use of epinephrine during neonatal cardiopulmonary resuscitation (CPR). However, newborns receiving epinephrine continue to have high rates of mortality and neurodevelopmental disability. The infrequent need for neonatal CPR, coupled with an inability to consistently anticip
Jan 162 min read


Meet the SURV1VE-2 - Trial Steering Committee
Leading the Way in Newborn Resuscitation Research Behind every major clinical trial is a dedicated team of experts guiding the vision,...
Aug 21, 20252 min read


The Conclusion of the 2nd HiLo-Trial DSMB review: Continue the Trial
The Data Safety Monitoring Board (DSMB) reviewed the data after 400 patients were enrolled at least 28 days old, to assess the safety of...
Oct 2, 20232 min read














