Chest Compression superimposed with Sustained Inflation – Translating preclinical findings into a neonatal clinical trial
From bench to bedside: translating physiology into clinical trials Cardiopulmonary resuscitation (CPR) at birth remains one of the most critical—and challenging—situations in neonatal care. While only a small proportion of newborns require CPR, the outcomes are sobering: mortality remains high, and survivors often face significant neurological injury. This blog highlights an important journey in neonatal resuscitation research— the development and translation of chest compres
2 days ago3 min read
Study Protocol SpotlightThe VOLT Trial: Volume-Targeted Mask Ventilation versus Pressure Ventilation in Preterm Infants
Providing effective and gentle respiratory support in the first minutes after birth is one of the most critical—and challenging—tasks in neonatal care. The VOLT trial (Volume-Targeted mask ventilation versus pressure ventilation in preterm infants) was designed to address a fundamental gap in delivery room practice: how to reliably deliver safe tidal volumes during positive pressure ventilation (PPV) immediately after birth. Why does this matter? When preterm infants fail to
Jan 293 min read
The Conclusion of the 2nd HiLo-Trial DSMB review: Continue the Trial
The Data Safety Monitoring Board (DSMB) reviewed the data after 400 patients were enrolled at least 28 days old, to assess the safety of...
Oct 2, 20232 min read
