Globally, 15 million newborns are born prematurely and 20% of them require support at birth; annually, ~1 million of these will die due to birth asphyxia. A significant proportion of these critically ill newborns survive with chronic lung disease or neurodevelopmental disabilities. This puts a heavy burden on health resources, as these infants require frequent hospital re-admission. Refining resuscitation techniques to decrease long-term complications has the potential to improve the quality of life for newborns and their families.
CSAR's focus is to 1) understand basic respiratory, cardiovascular and neurological changes during the fetal to neonatal transition and 2) improve diagnoses, mitigate risk and improve survival and quality of life for newborns. Improving neonatal outcomes requires specialized, interdisciplinary centres such as CSAR, which combine basic, clinical and translational research.